Basic Information
VIS ID
TVIS30004299
Fusion event
HIV-ELF4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
129235832/130101857 (Hg38)
End
129235832/130101857 (Hg38)
Orient
-
Location type
Intronic
Target gene
ELF4
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-877-5p ; hsa-mir-615-3p ; hsa-mir-505-3p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-let-7f-5p ; hsa-mir-331-5p ; hsa-mir-4666a-5p ; hsa-mir-8068 ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-5087 ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-298 ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-4678 ; hsa-mir-376c-3p
Nearest miRNA
hsa-let-7f-2/Upstream/8730804; hsa-mir-105-1/Downstream/4067521;
Nearest TSS
ENST00000429181/Upstream/20425; ENST00000257017/Downstream/8504;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/41129, chrX-CpG: 189/Downstream/7842
Nearest cancer related gene
ELF4(OG, No orient, 0)
Upstream sequence
cattgcactccagcctgggcgacaagagggaaactccgtctcaaaaaacaaaacaaaacaaaacaaaacaaaacaaaacaaaacaaaaACAAGGCCAgac
Downstream sequence
tgggcgcagtggctcacgccggtaatcccagcactttgggaggccaacgccagtggatcatttgaggtcaggagtttgagaccagcctggccaacatggt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate