Basic Information
VIS ID
TVIS30004337
Fusion event
HIV-MPL integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.2
Reference genome
GRCh37/hg19
Start
43810965/43345294 (Hg38)
End
43810965/43345294 (Hg38)
Orient
-
Location type
Intronic
Target gene
MPL
miRNAs that regulate target gene
hsa-mir-28-5p ; hsa-let-7c-5p ; hsa-let-7e-5p ; hsa-let-7a-5p ; hsa-let-7d-5p ; hsa-let-7f-5p ; hsa-mir-98-5p ; hsa-mir-151a-5p ; hsa-mir-708-3p ; hsa-mir-1-3p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6134 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-1247-3p ; hsa-mir-4257 ; hsa-mir-135b-5p ; hsa-mir-135a-5p
Nearest miRNA
hsa-mir-12136/Upstream/173582; hsa-mir-101-1/Downstream/19354;
Nearest TSS
ENST00000473358/Upstream/7445; ENST00000643351/Downstream/3969;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/40085, chr1-CpG: 76/Downstream/3340
Nearest cancer related gene
MPL(OG, No orient, 0)
Upstream sequence
aggggaaaaggagggggagaaaagtaagtaaagaaataaaggaacaaagttataatagagactaaaggggggcgtgtggtgggtggggggtgggtgttgc
Downstream sequence
taatttagactgagtggccaggaaaagcctcaccagggaggtgacagataagccgagatctaaatggcaagaaggaatgagtcacatgaagacctacagt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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