Basic Information
VIS ID
TVIS30004357
Fusion event
HIV-PRUNE1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
150990596/151018120 (Hg38)
End
150990596/151018120 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1F
Target gene
PRUNE1
miRNAs that regulate target gene
hsa-mir-218-5p
Nearest miRNA
hsa-mir-101-1/Upstream/466106; hsa-mir-1182/Downstream/527676;
Nearest TSS
ENST00000473358/Upstream/9590; ENST00000368934/Downstream/6622;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/9504, chr1-CpG: 38/Downstream/29615
Upstream sequence
ctttgctgagtctcatgccaccatccataaaaactaaaatgatattttgcagtgttgctgtgaggaaaaaagtgagcaaatatatttcgagggatatgta
Downstream sequence
aaccataaagcaatattcaaaCAGTTTATTACTGAGTTCCGTATAGGTATCAGTGATCTAGTGTGTATTCCTCTGCCCAGGTTAGTTCTTGAGGACTAAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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