Basic Information
VIS ID
TVIS30004385
Fusion event
HIV-WBP1L integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q24.32
Reference genome
GRCh37/hg19
Start
104517631/102757874 (Hg38)
End
104517631/102757874 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
WBP1L
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-19b-3p ; hsa-mir-760 ; hsa-mir-615-3p ; hsa-mir-320a ; hsa-mir-2110 ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-6733-5p ; hsa-mir-6739-5p ; hsa-mir-3153 ; hsa-mir-8089 ; hsa-mir-4700-5p ; hsa-mir-4667-5p ; hsa-mir-582-3p
Nearest miRNA
hsa-mir-107/Upstream/321290; hsa-mir-1307/Downstream/636379;
Nearest TSS
ENST00000439456/Upstream/13904; ENST00000369889/Downstream/18375;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/42920, chr10-CpG: 28/Downstream/96369
Upstream sequence
ctgtgttgaccaagctggtcttgaactcctgacctccagtgatcctcctgcctcggcctcccaaagtgctgggattacagcatgagccactgtacctgcc
Downstream sequence
cTCCCCCCCCCCCttttttttttttttttgagacagagtctcactctgtcacccaggctgaagtgcaatggcacgatctcggctcactgtaacctccgct
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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