Basic Information
VIS ID
TVIS30004391
Fusion event
HIV-HRAS integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
GRCh37/hg19
Start
532534/532534 (Hg38)
End
532534/532534 (Hg38)
Orient
-
Location type
UTR3
Target gene
HRAS
miRNAs that regulate target gene
hsa-let-7a-5p ; hsa-mir-143-3p ; hsa-mir-181a-5p ; hsa-let-7b-5p ; hsa-mir-181d-5p ; hsa-mir-615-3p ; hsa-mir-139-5p ; hsa-mir-663a ; hsa-mir-1199-3p ; hsa-mir-1268a ; hsa-mir-1268b ; hsa-mir-1908-3p ; hsa-mir-4292 ; hsa-mir-4467 ; hsa-mir-4632-3p ; hsa-mir-541-3p ; hsa-mir-585-3p ; hsa-mir-654-5p ; hsa-mir-6770-3p ; hsa-mir-6786-5p ; hsa-mir-6791-5p
Nearest miRNA
hsa-mir-6743/Upstream/323128; hsa-let-7a-2/Downstream/35555;
Nearest TSS
ENST00000527297/Upstream/3627; ENST00000270115/Downstream/1061;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/12237, chr11-CpG: 274/Downstream/2157
Nearest cancer related gene
HRAS(OG, No orient, 0)
Upstream sequence
ccttccttccttgcttccgtccttccttcctcctccttccGTCTGCACCTCCTTCCTGCATCCGGCACCTCCATGTCCTGAGCTTGTGCTGGGCGGGGCA
Downstream sequence
CAAGGGAGGCTGCTGACCGCAGGCCAGGAGACCGGCAGGGGCGGGGAGCCGGGGTCATCCGGTGGGCGTGGCGGCCGCCCTGGGAGTCCCCCTCACCTGC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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