Basic Information
VIS ID
TVIS30004407
Fusion event
HIV-VPS51 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
64869634/65102162 (Hg38)
End
64869634/65102162 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
VPS51
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-324-5p ; hsa-mir-182-5p ; hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-4697-5p ; hsa-mir-4488 ; hsa-mir-1237-5p ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-566 ; hsa-mir-4767 ; hsa-mir-668-5p ; hsa-mir-6499-5p ; hsa-mir-4787-5p ; hsa-mir-6773-5p ; hsa-mir-6724-5p ; hsa-mir-1226-3p ; hsa-mir-296-5p ; hsa-mir-218-5p ; hsa-mir-145-5p
Nearest miRNA
hsa-mir-10392/Upstream/83592; hsa-let-7a-2/Downstream/27754;
Nearest TSS
ENST00000527297/Upstream/5409; ENST00000531146/Downstream/3246;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/5654, chr11-CpG: 95/Downstream/5500
Upstream sequence
aggctagagtgcagtggcccaatcggctcactgcaacctccgcctccggggttcaagtgattctcctgtcttaggcttccaagtacctgggattacaggc
Downstream sequence
acctgccaccacacttggctaattattgtattttcagtagagacgggatttcaccatgttggtcaggcaggtgacctcaggtgatccacctgccttggcc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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