Basic Information
VIS ID
TVIS30004422
Fusion event
HIV-PITPNM1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
67269558/67502087 (Hg38)
End
67269558/67502087 (Hg38)
Orient
-
Location type
splicing
Fragile sites / regions
FRA11H
Target gene
PITPNM1
miRNAs that regulate target gene
hsa-mir-221-3p ; hsa-mir-432-5p
Nearest miRNA
hsa-mir-10392/Upstream/11772; hsa-let-7a-2/Downstream/530777;
Nearest TSS
ENST00000527297/Upstream/1679; ENST00000489040/Downstream/541;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/6843, chr11-CpG: 149/Downstream/2101
Upstream sequence
GTGGCCCTCGGCCCGTCTTGACCGAGTGATAAAGCCGGGGGTCCTCTTCTGCTTTGTACTCGCCTGGGGCCACTGCATCCCGCACGATGTCGATGGTGTC
Downstream sequence
TGAGGGAGTTCGGCAAGCATTGAGCAGCGCCAGCCCCTTTGAGCCCCCGCTCCTGGCACCCTCTTGGGACTGGATGACAGTTCCCGTCCTTTTGCAGACA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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