Basic Information
VIS ID
TVIS30004431
Fusion event
HIV-BIRC2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
102233769/102363038 (Hg38)
End
102233769/102363038 (Hg38)
Orient
+
Location type
Intronic
Target gene
BIRC2
miRNAs that regulate target gene
hsa-mir-204-5p ; hsa-mir-124-3p ; hsa-mir-34a-5p
Nearest miRNA
hsa-mir-10392/Upstream/843133; hsa-let-7a-2/Downstream/1486868;
Nearest TSS
ENST00000527297/Upstream/296; ENST00000528717/Downstream/86414;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/15522, chr11-CpG: 106/Downstream/88760
Nearest cancer related gene
BIRC2(OG, No orient, 0)
Upstream sequence
GAGATTCAAGGTAGATATCCTCATCTTCTTGAACAGGTAAATACATTTTTAAAATTAACAACATTGAATTCTGCTTTATAATAACAAAAATATTAttagg
Downstream sequence
ttggtataaaagtgatcatgatttttgccattgaaagtcatggccaaaaccgtgatcacttttgtaccaacctaTATTAGAAGTTATGCTTATTTCTCTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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