Basic Information
VIS ID
TVIS30004472
Fusion event
HIV-DIABLO integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.31
Reference genome
GRCh37/hg19
Start
122694803/122210256 (Hg38)
End
122694803/122210256 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
DIABLO
miRNAs that regulate target gene
hsa-mir-29a-3p ; hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-34a-5p ; hsa-mir-218-5p ; hsa-mir-6741-5p ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-1294 ; hsa-mir-4316 ; hsa-mir-609 ; hsa-mir-4455 ; hsa-mir-6772-5p ; hsa-mir-555 ; hsa-mir-1251-3p ; hsa-mir-202-3p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-646 ; hsa-mir-2278 ; hsa-mir-4506
Nearest miRNA
hsa-let-7i/Upstream/765904; hsa-mir-3612/Downstream/485651;
Nearest TSS
ENST00000382841/Upstream/5656; ENST00000539034/Downstream/7533;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/5697, chr12-CpG: 127/Downstream/15251
Nearest cancer related gene
DIABLO(TSG, No orient, 0)
Upstream sequence
tcgttttggtgctgccctagtccagtttgggatcggggctatgctggcttcatacagtagtaagaggaggcttgtcattactttctttgcgctggtacac
Downstream sequence
ttacagtaacataggtattatagttttggaagatttgataaaactctcccacgaaacatcctaggccctggtgtccattttggggacatcaaaatcttcg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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