Basic Information
VIS ID
TVIS30004484
Fusion event
HIV-KLHL1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
70522654/69948522 (Hg38)
End
70522654/69948522 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13B
Target gene
KLHL1
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1297/Upstream/3730198; hsa-mir-1267/Downstream/7749490;
Nearest TSS
ENST00000623511/Upstream/637189; ENST00000424524/Downstream/158691;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/963350, chr13-CpG: 42/Downstream/159078
Upstream sequence
cacaaataattggttttgaTCCTATAAACTGCTTATAAAATTGGAGTCACCCTCCTCTGATTCAAGTGGGGGACTAAACGGGGAATACTTTTTAAATAGG
Downstream sequence
GTTCCAATAAGGTGTGCTACATTTATCTACAATCACATCTTAAGTAAATGCTAAGGCCACTAAATCTTCCAAATATGTATGAGTAGACTTAAACTCTGTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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