Basic Information
VIS ID
TVIS30004507
Fusion event
HIV-CTDSPL2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q15.3
Reference genome
GRCh37/hg19
Start
44752749/44460551 (Hg38)
End
44752749/44460551 (Hg38)
Orient
-
Location type
Intronic
Target gene
CTDSPL2
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-877-3p ; hsa-mir-193b-3p ; hsa-mir-100-5p ; hsa-mir-374a-5p ; hsa-mir-18b-3p ; hsa-mir-3157-3p ; hsa-mir-4744 ; hsa-mir-4709-3p ; hsa-mir-3127-5p ; hsa-mir-4772-5p ; hsa-mir-383-5p ; hsa-mir-4699-5p ; hsa-mir-539-5p ; hsa-mir-3918 ; hsa-mir-4761-3p ; hsa-mir-140-3p ; hsa-mir-618 ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p
Nearest miRNA
hsa-mir-1233-1/Upstream/666792; hsa-mir-10393/Downstream/257293;
Nearest TSS
ENST00000557528/Upstream/1548; ENST00000561189/Downstream/30441;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/32611, chr15-CpG: 131/Downstream/75888
Upstream sequence
TTGATTGTGTGTAGTTTTTTTATGACTTTACTATTTTTGTGTTCTTAGAATAATTATTTATATGGTAAATTTTTCATTATAATGGAAGTGTATTACTTTC
Downstream sequence
TTAAGCAGAAAAATAAATTACTGGCTGACTTGTTCATAGGGATAGATTTTGTTGTAATAGAATTAACAAAGCCTAATTACTGTAAGTCACTGGGCAAGAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate