Basic Information
VIS ID
TVIS30004516
Fusion event
HIV-DENND4A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
65985702/65693364 (Hg38)
End
65985702/65693364 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA15A
Target gene
DENND4A
miRNAs that regulate target gene
hsa-mir-92b-3p ; hsa-mir-25-3p
Nearest miRNA
hsa-mir-10393/Upstream/930849; hsa-mir-11181/Downstream/25882;
Nearest TSS
ENST00000557528/Upstream/2826; ENST00000563580/Downstream/8437;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/82032, chr15-CpG: 104/Downstream/98137
Upstream sequence
AAGAAATAGATATGGCTGGTGTTTCTCTTCCCATTCTTTTTGGCTTGATCGAATAGGTGATATGGGGAGTTACCAGTGGCTATACTGTAATCATGGTTAG
Downstream sequence
GTCAAAAGAACTGATGGCAAAGCCCCTGAGCCAACATTTAGAGCAAGTGCTTACCTCTGAATTTCCTGTTTGAGAAAAATAAACTGCAACTTCTTTAAGC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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