Basic Information
VIS ID
TVIS30004572
Fusion event
HIV-RBL2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
53480362/53446450 (Hg38)
End
53480362/53446450 (Hg38)
Orient
+
Location type
Intronic
Target gene
RBL2
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-335-5p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-106a-5p ; hsa-mir-92b-3p
Nearest miRNA
hsa-mir-1225/Upstream/2704073; hsa-mir-11401/Downstream/2799070;
Nearest TSS
ENST00000527434/Upstream/669; ENST00000561512/Downstream/15319;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/11153, chr16-CpG: 96/Downstream/56139
Nearest cancer related gene
RBL2(TSG, No orient, 0)
Upstream sequence
atggcagtgctggaactaaatctaatctaatcttctccacggaatttcgttcttctgggcaccttgttaGAATAAGGCTGTTGGGAGGTGGAGACCACAG
Downstream sequence
ATTTCTTGTCTAAAAGTTGTCAGAGGTTTTGGTAGAAAAGCCAAGCTTAAAGCAGGTCTGAAACTTGGCAGACTACTTGGCAATATACAACAGGTACTCT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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