Basic Information
VIS ID
TVIS30004585
Fusion event
HIV-WDR59 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
74929245/74895347 (Hg38)
End
74929245/74895347 (Hg38)
Orient
+
Location type
Intronic
Target gene
WDR59
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-17-3p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-607 ; hsa-mir-4753-3p ; hsa-mir-3671 ; hsa-mir-130b-5p ; hsa-mir-6873-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-4482-3p ; hsa-mir-7159-3p ; hsa-mir-4775 ; hsa-mir-6789-3p ; hsa-mir-4707-3p ; hsa-mir-138-2-3p ; hsa-mir-4735-5p ; hsa-mir-4258 ; hsa-mir-6872-3p ; hsa-mir-590-3p
Nearest miRNA
hsa-mir-1225/Upstream/4864925; hsa-mir-11401/Downstream/1973589;
Nearest TSS
ENST00000527434/Upstream/1407; ENST00000568511/Downstream/8673;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/120259, chr16-CpG: 65/Downstream/89151
Upstream sequence
AACCCGTTTGATCtttttatttttttttcttttgagacagagtcttgctctgttgctgaggctggagtgcagtggtgtgatcttggctcactgaaatctc
Downstream sequence
cgcctccggggttcaagtgattctcctgcctcagcctcccgagtagctgggattacaggcatgcaccatcatactcagctaatttttgtatttttagtag
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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