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Viral Integration Site DataBase
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TVIS30004595
Basic Information
VIS ID
TVIS30004595
Fusion event
HIV-RFLNB integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
295337/445546 (Hg38)
End
295337/445546 (Hg38)
Orient
+
Location type
Intronic
Target gene
RFLNB
miRNAs that regulate target gene
hsa-mir-193b-3p
;
hsa-mir-192-5p
;
hsa-mir-3157-5p
;
hsa-mir-4691-3p
;
hsa-mir-888-5p
;
hsa-mir-1827
;
hsa-mir-3664-3p
;
hsa-mir-3929
;
hsa-mir-3934-3p
;
hsa-mir-4419b
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4478
;
hsa-mir-4649-3p
;
hsa-mir-4695-5p
;
hsa-mir-4722-5p
;
hsa-mir-4768-3p
;
hsa-mir-485-5p
;
hsa-mir-5192
;
hsa-mir-665
;
hsa-mir-6808-5p
;
hsa-mir-6884-5p
;
hsa-mir-6893-5p
;
hsa-mir-7160-5p
;
hsa-mir-767-3p
;
hsa-mir-940
Nearest miRNA
hsa-mir-10226/Downstream/576930;
Nearest TSS
ENST00000595228/Upstream/31353;
ENST00000571282/Downstream/393;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/2005
,
chr17-CpG: 62/Downstream/44032
Upstream sequence
CTAGTGAAATTATACTATGAGACAAGGTTAAAAGACCTCAGAGACTGGGTTGGCAGGTAAGGGAGTAGGGTACAGCAGCTTCTGGAAAGAAGAATTAATA
Downstream sequence
TTTGACAAAATTGTAACCCTCTGACAGCcatgatacatgaattgcaaaaagaaaatgcagaactttatacataacatgatctcatttttattttaatttt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Bcl-2 transduced CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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