Basic Information
VIS ID
TVIS30004614
Fusion event
HIV-AURKB integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
8110743/8207425 (Hg38)
End
8110743/8207425 (Hg38)
Orient
+
Location type
Intronic
Target gene
AURKB
miRNAs that regulate target gene
hsa-mir-24-3p ; hsa-let-7b-5p ; hsa-mir-16-5p ; hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-125b-5p ; hsa-mir-148a-3p ; hsa-mir-92a-3p ; hsa-let-7a-5p ; hsa-let-7e-5p ; hsa-let-7i-5p
Nearest miRNA
hsa-mir-1253/Upstream/20421; hsa-mir-10226/Downstream/3874474;
Nearest TSS
ENST00000595228/Upstream/58; ENST00000585183/Downstream/800;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/17037, chr17-CpG: 27/Downstream/2889
Upstream sequence
AGAGGACGCCCAATCTCAAAGTCATCAATTGTGAAGTGCCGCCTGCTTAGAAAGTGGAGGAAGGCAACTCAGAACCGGTTTTGGTTATTAAGAGGTTTGC
Downstream sequence
TTTCTCTCTGCTTCCTCATCCCATCCTGTCCTCCGCCCCACTTGTCTTCATCCCTACTCCTCCCGTGCTTAGGTTTTATCTCCCCGACTTCCTGCCTGTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate