Basic Information
VIS ID
TVIS30004656
Fusion event
HIV-UBE2O integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
74437434/76441352 (Hg38)
End
74437434/76441352 (Hg38)
Orient
+
Location type
Intronic
Target gene
UBE2O
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-877-3p ; hsa-mir-744-5p ; hsa-mir-30c-1-3p ; hsa-mir-505-3p ; hsa-mir-328-3p ; hsa-mir-93-5p ; hsa-mir-432-3p ; hsa-mir-485-5p
Nearest miRNA
hsa-mir-10226/Upstream/343276; hsa-mir-1250/Downstream/295098;
Nearest TSS
ENST00000595228/Upstream/36120; ENST00000585649/Downstream/11789;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/54920, chr17-CpG: 93/Downstream/10954
Upstream sequence
CTTGGATTGGGTGTGTTATACTCAAAACAACTACCATATTTACATCCTAAAATGAAATGAAATCAAATGAAACTTCTTAGCAACAGCAGTGCATTAATAA
Downstream sequence
TAACCACCAGCAAGCAATGGGGAGGAAGAAAGAGGCAAGCCTTTCTAACACTAAAGCACTGGCGGATGATGAGTCCGCCTCATCCCTTTCCTGCCCCTCC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate