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Viral Integration Site DataBase
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TVIS30004686
Proximate region of VIS (GRCh38)
VIS
Enhancer
Enhancer/Promoter
Promoter
Gene
51186531
50968019
51058144
51028394
51085045
51027691
51032201
51036401
51040400
51069546
51071561
51041201
51042800
51067561
51068907
51053415
51054421
51035801
51036200
51044801
51045000
51051211
51051380
51050991
51051140
51051431
51051580
51077275
Basic Information
VIS ID
TVIS30004686
Fusion event
HIV-SMAD4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
48603645/51077275 (Hg38)
End
48603645/51077275 (Hg38)
Orient
+
Location type
Intronic
Target gene
SMAD4
miRNAs that regulate target gene
hsa-mir-26a-5p
;
hsa-mir-483-3p
;
hsa-mir-18a-5p
;
hsa-mir-17-5p
;
hsa-mir-19a-3p
;
hsa-mir-20a-5p
;
hsa-mir-92a-3p
;
hsa-mir-203a-3p
;
hsa-mir-421
;
hsa-mir-146a-5p
;
hsa-mir-224-5p
;
hsa-mir-125a-5p
;
hsa-mir-125b-5p
;
hsa-mir-199a-5p
;
hsa-mir-130a-3p
;
hsa-mir-301a-3p
;
hsa-mir-454-3p
;
hsa-mir-182-5p
;
hsa-mir-130b-3p
;
hsa-mir-155-5p
;
hsa-mir-186-5p
;
hsa-mir-93-5p
;
hsa-mir-19b-3p
;
hsa-mir-204-5p
;
hsa-mir-1260b
;
hsa-mir-205-5p
;
hsa-mir-452-5p
;
hsa-mir-145-5p
;
hsa-mir-183-5p
;
hsa-mir-106a-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-519c-3p
;
hsa-mir-526b-3p
;
hsa-mir-519b-3p
;
hsa-mir-519d-3p
;
hsa-mir-519a-3p
;
hsa-mir-551b-5p
;
hsa-mir-548c-3p
;
hsa-mir-301b-3p
;
hsa-mir-548f-5p
;
hsa-mir-548g-5p
;
hsa-mir-548t-5p
;
hsa-mir-548x-5p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-548aj-5p
;
hsa-mir-548aw
;
hsa-mir-548az-5p
;
hsa-mir-6715b-3p
;
hsa-mir-4528
;
hsa-mir-34a-5p
;
hsa-mir-154-5p
;
hsa-mir-34c-5p
;
hsa-mir-449a
;
hsa-mir-449b-5p
;
hsa-mir-8062
;
hsa-mir-4668-5p
;
hsa-mir-1468-3p
;
hsa-mir-302a-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-888-5p
;
hsa-mir-6715a-3p
;
hsa-mir-5701
;
hsa-mir-616-3p
;
hsa-mir-548au-3p
;
hsa-mir-8076
;
hsa-mir-670-3p
;
hsa-mir-4799-5p
;
hsa-mir-27b-3p
;
hsa-mir-27a-3p
;
hsa-mir-513a-5p
;
hsa-mir-6731-3p
;
hsa-mir-6891-3p
;
hsa-mir-6072
;
hsa-mir-5582-3p
;
hsa-mir-144-3p
;
hsa-mir-574-3p
;
hsa-mir-34a-3p
;
hsa-mir-31-5p
;
hsa-mir-144-5p
;
hsa-mir-3661
;
hsa-mir-4783-5p
;
hsa-mir-574-5p
;
hsa-mir-631
;
hsa-mir-6867-5p
;
hsa-mir-933
Nearest miRNA
hsa-mir-1-2/Upstream/950712; hsa-mir-122/Downstream/2159826;
Nearest TSS
ENST00000575820/Upstream/24;
ENST00000578152/Downstream/119484;
Nearest CpG islands
None/Target,
chr18-CpG: 67/Upstream/46312
,
chr18-CpG: 156/Downstream/118885
Nearest cancer related gene
SMAD4
(TSG, No orient, 0)
Upstream sequence
AAAGTATGCTAAACATGGAGAGAAAACTAAGTGAGGGTGGTATTTTGATAACTTGTAGACTTTTTTTTAATTTTAGGGTAAAATTGAACtgtgtgccagg
Downstream sequence
tttcacactgatggggaattttttactgcagagttaaactcctgactatagacttttatgatggaaacacgtggcacCCATCTTCCACGTCTGAAGGCAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Bcl-2 transduced CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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