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TVIS30004686
Basic Information
VIS ID
TVIS30004686
Fusion event
HIV-SMAD4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
48603645/51077275 (Hg38)
End
48603645/51077275 (Hg38)
Orient
+
Location type
Intronic
Target gene
SMAD4
miRNAs that regulate target gene
hsa-mir-26a-5p
;
hsa-mir-483-3p
;
hsa-mir-18a-5p
;
hsa-mir-17-5p
;
hsa-mir-19a-3p
;
hsa-mir-20a-5p
;
hsa-mir-92a-3p
;
hsa-mir-203a-3p
;
hsa-mir-421
;
hsa-mir-146a-5p
;
hsa-mir-224-5p
;
hsa-mir-125a-5p
;
hsa-mir-125b-5p
;
hsa-mir-199a-5p
;
hsa-mir-130a-3p
;
hsa-mir-301a-3p
;
hsa-mir-454-3p
;
hsa-mir-182-5p
;
hsa-mir-130b-3p
;
hsa-mir-155-5p
;
hsa-mir-186-5p
;
hsa-mir-93-5p
;
hsa-mir-19b-3p
;
hsa-mir-204-5p
;
hsa-mir-1260b
;
hsa-mir-205-5p
;
hsa-mir-452-5p
;
hsa-mir-145-5p
;
hsa-mir-183-5p
;
hsa-mir-106a-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-519c-3p
;
hsa-mir-526b-3p
;
hsa-mir-519b-3p
;
hsa-mir-519d-3p
;
hsa-mir-519a-3p
;
hsa-mir-551b-5p
;
hsa-mir-548c-3p
;
hsa-mir-301b-3p
;
hsa-mir-548f-5p
;
hsa-mir-548g-5p
;
hsa-mir-548t-5p
;
hsa-mir-548x-5p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-548aj-5p
;
hsa-mir-548aw
;
hsa-mir-548az-5p
;
hsa-mir-6715b-3p
;
hsa-mir-4528
;
hsa-mir-34a-5p
;
hsa-mir-154-5p
;
hsa-mir-34c-5p
;
hsa-mir-449a
;
hsa-mir-449b-5p
;
hsa-mir-8062
;
hsa-mir-4668-5p
;
hsa-mir-1468-3p
;
hsa-mir-302a-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-888-5p
;
hsa-mir-6715a-3p
;
hsa-mir-5701
;
hsa-mir-616-3p
;
hsa-mir-548au-3p
;
hsa-mir-8076
;
hsa-mir-670-3p
;
hsa-mir-4799-5p
;
hsa-mir-27b-3p
;
hsa-mir-27a-3p
;
hsa-mir-513a-5p
;
hsa-mir-6731-3p
;
hsa-mir-6891-3p
;
hsa-mir-6072
;
hsa-mir-5582-3p
;
hsa-mir-144-3p
;
hsa-mir-574-3p
;
hsa-mir-34a-3p
;
hsa-mir-31-5p
;
hsa-mir-144-5p
;
hsa-mir-3661
;
hsa-mir-4783-5p
;
hsa-mir-574-5p
;
hsa-mir-631
;
hsa-mir-6867-5p
;
hsa-mir-933
Nearest miRNA
hsa-mir-1-2/Upstream/950712; hsa-mir-122/Downstream/2159826;
Nearest TSS
ENST00000575820/Upstream/24;
ENST00000578152/Downstream/119484;
Nearest CpG islands
None/Target,
chr18-CpG: 67/Upstream/46312
,
chr18-CpG: 156/Downstream/118885
Nearest cancer related gene
SMAD4
(TSG, No orient, 0)
Upstream sequence
AAAGTATGCTAAACATGGAGAGAAAACTAAGTGAGGGTGGTATTTTGATAACTTGTAGACTTTTTTTTAATTTTAGGGTAAAATTGAACtgtgtgccagg
Downstream sequence
tttcacactgatggggaattttttactgcagagttaaactcctgactatagacttttatgatggaaacacgtggcacCCATCTTCCACGTCTGAAGGCAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Bcl-2 transduced CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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