Basic Information
VIS ID
TVIS30004694
Fusion event
HIV-PWWP3A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1371377/1371378 (Hg38)
End
1371377/1371378 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
PWWP3A
miRNAs that regulate target gene
hsa-mir-1199-5p ; hsa-mir-1225-3p ; hsa-mir-1233-3p ; hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-1324 ; hsa-mir-3943 ; hsa-mir-4313 ; hsa-mir-4319 ; hsa-mir-574-3p ; hsa-mir-6751-3p ; hsa-mir-6847-3p
Nearest miRNA
hsa-mir-1302-11/Upstream/557725; hsa-let-7e/Downstream/444781;
Nearest TSS
ENST00000633603/Upstream/55; ENST00000591627/Downstream/721;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/95, chr19-CpG: 65/Downstream/5177
Nearest cancer related gene
PWWP3A(OG, No orient, 0)
Upstream sequence
AGCCGCTTACTTGACCCCTGTGCAGAGATGGAGCTGCTTAGAAGCTGTCAGCACCAGGGGGTGCGAACTCCCTCCCTACTGCGGGCGCAcagatgcttcc
Downstream sequence
cagcctcggtgggtcagtcctgggaaacccactgcgagttggaaattcccaagtcagaatcgcatttagtacccagataaacccactgtaagttgaaaaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate