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VISDB
Viral Integration Site DataBase
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TVIS30004731
Proximate region of VIS (GRCh38)
VIS
Enhancer
Enhancer/Promoter
Promoter
Gene
17392098
17292131
17310236
17292609
17306843
17309518
17323301
17323223
17334829
17334920
17342735
17307912
17313543
17302025
17306988
17326150
17330824
17321549
17325425
17336092
17338619
17333041
17335481
17295686
17297644
17291846
17293541
17340044
17341673
17316770
17318279
17293601
17294781
17338772
17339186
17332692
17332901
17339252
17339421
17341972
Basic Information
VIS ID
TVIS30004731
Fusion event
HIV-GTPBP3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
17452781/17341972 (Hg38)
End
17452781/17341972 (Hg38)
Orient
-
Location type
UTR3
Fragile sites / regions
FRA19B
Target gene
GTPBP3
miRNAs that regulate target gene
hsa-let-7b-5p
;
hsa-mir-3622a-3p
;
hsa-mir-3622b-3p
;
hsa-mir-4682
;
hsa-mir-2681-5p
;
hsa-mir-4777-5p
;
hsa-mir-526a
;
hsa-mir-523-5p
;
hsa-mir-522-5p
;
hsa-mir-520c-5p
;
hsa-mir-519c-5p
;
hsa-mir-519b-5p
;
hsa-mir-519a-5p
;
hsa-mir-518f-5p
;
hsa-mir-518e-5p
;
hsa-mir-518d-5p
;
hsa-mir-6765-3p
;
hsa-mir-5694
;
hsa-mir-383-5p
;
hsa-mir-4262
;
hsa-mir-181d-5p
;
hsa-mir-181c-5p
;
hsa-mir-181b-5p
;
hsa-mir-181a-5p
;
hsa-mir-181a-2-3p
;
hsa-mir-377-5p
;
hsa-mir-455-3p
;
hsa-mir-6086
;
hsa-mir-6516-5p
Nearest miRNA
hsa-mir-10395/Upstream/1892364; hsa-let-7e/Downstream/940105;
Nearest TSS
ENST00000633603/Upstream/1026;
ENST00000597592/Downstream/18960;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/3738
,
chr19-CpG: 41/Downstream/9940
Upstream sequence
AGATTCAGGCCCTGGAATGGGGCTGAATGGAGGTCCCGTTCGACCCTTGATGCTGGGGCATCCGGGTTGGGATGGAGATAGGAGGATCTCAGTATATTTG
Downstream sequence
TTTCGTAGTTTTTTATTTATTTTGCAAATACCAAAGGAATGTAAAAAAAACTCAGGTGATCTAGAAGTGTTTATTTTcttcccttcccttcccttccctt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Bcl-2 transduced CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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