Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene5047239550329653503829825038420450418016503584775036583050365880503693315038304850386200503569995035998350375783503778595036816450369949503866015038820050373759503753445036250850363899503719575037296950361404503615535036464450364793503658475036590650401024
Basic Information
VIS ID
TVIS30004760
Fusion event
HIV-POLD1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50904281/50401024 (Hg38)
End
50904281/50401024 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
POLD1
miRNAs that regulate target gene
hsa-mir-24-3p ; hsa-mir-193b-3p ; hsa-mir-1-3p ; hsa-mir-34a-5p ; hsa-mir-324-5p ; hsa-let-7e-5p
Nearest miRNA
hsa-mir-10395/Upstream/467887; hsa-let-7e/Downstream/805905;
Nearest TSS
ENST00000633603/Upstream/16651; ENST00000596425/Downstream/2188;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/16348, chr19-CpG: 48/Downstream/1196
Upstream sequence
tgacctcgtgatccgcccgcctcagcctcccaaagtgctgagattacaggcttgagccaccgcgcccggccTGGCTAACTTTTAAAAATATACTTTTGGG
Downstream sequence
CCCGGCATGGTGGCTcacttttggaggctgaggcaggctgatcacttgaggacaggagttcaagaccagcctggccaacatggtgaaaccccgtctctac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate