Basic Information
VIS ID
TVIS30004778
Fusion event
HIV-FBXO11 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
48103041/47875902 (Hg38)
End
48103041/47875902 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
FBXO11
miRNAs that regulate target gene
hsa-mir-181a-5p ; hsa-mir-101-3p ; hsa-mir-26b-5p ; hsa-mir-21-5p ; hsa-mir-421 ; hsa-mir-27b-5p ; hsa-mir-4538 ; hsa-mir-4453 ; hsa-mir-26a-5p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-543
Nearest miRNA
hsa-mir-1301/Upstream/498132; hsa-mir-10b/Downstream/1183701;
Nearest TSS
ENST00000437798/Upstream/39940; ENST00000432064/Downstream/12817;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/91598, chr2-CpG: 89/Downstream/29243
Upstream sequence
ggtataccaagggTTTAGCCTTCTTCATTCTCTTATTTTCATTCCTTTAGTTCTGCTGGTCTGGAAGACATCTATTTTATTTCTATTCCTTTTGTGGTTA
Downstream sequence
CTCAGGTTAAAAAAGAAAAGCAGCAGCAGCAGCAAACATGTATAGAGTAGTACTAATCAGTGgctttatatgtatttcacttaatcctccccacaacaac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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