Basic Information
VIS ID
TVIS30004779
Fusion event
HIV-PSME4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.2
Reference genome
GRCh37/hg19
Start
54159651/53932514 (Hg38)
End
54159651/53932514 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2D ; FRA2H
Target gene
PSME4
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-155-5p ; hsa-mir-98-5p ; hsa-mir-30a-5p ; hsa-mir-16-5p ; hsa-mir-1303 ; hsa-let-7e-5p ; hsa-mir-218-5p ; hsa-mir-7856-5p ; hsa-mir-4477b ; hsa-mir-142-3p ; hsa-mir-4326 ; hsa-mir-6073 ; hsa-mir-20b-3p ; hsa-mir-4255 ; hsa-mir-1183 ; hsa-mir-651-3p
Nearest miRNA
hsa-mir-1301/Upstream/83309; hsa-mir-10b/Downstream/2050453;
Nearest TSS
ENST00000437798/Upstream/23671; ENST00000606082/Downstream/655;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/72385, chr2-CpG: 81/Downstream/37997
Upstream sequence
CTATGCTTCTAAGGCATTTTTGTTACCATTTTTTTGCAAAAATGAGCCATGTTGTCAACAGTTACCACATCaatattatttatttaatttatatGCTCTC
Downstream sequence
CCACACAGTAATTTAATTTAAATGTAAGCATTTACATATAGCTAAAGCTATGAAGGACAGAAAATGTATTACAGGTCACACAATAGGCAATAGTCAAGGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate