Basic Information
VIS ID
TVIS30004796
Fusion event
HIV-PPIG integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
170477224/169620714 (Hg38)
End
170477224/169620714 (Hg38)
Orient
-
Location type
Intronic
Target gene
PPIG
miRNAs that regulate target gene
hsa-let-7e-5p ; hsa-mir-525-3p ; hsa-mir-510-3p ; hsa-mir-3161 ; hsa-mir-4738-3p ; hsa-mir-4310 ; hsa-mir-7157-5p ; hsa-mir-580-5p ; hsa-mir-5583-5p ; hsa-mir-6838-5p ; hsa-mir-3129-3p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-340-5p ; hsa-mir-4795-5p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-6507-5p ; hsa-mir-186-5p ; hsa-mir-3133
Nearest miRNA
hsa-mir-128-1/Upstream/1037696; hsa-mir-10b/Downstream/5546919;
Nearest TSS
ENST00000437798/Upstream/16674; ENST00000466142/Downstream/10136;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/35883, chr2-CpG: 59/Downstream/73559
Upstream sequence
ATAAATTATTTTTTCTTTAAGCACTACTTAGATTCAGAAGCATCCAACATGTTTGAGAAACTTCTTTTATTTAGACGAGACCATTTGATGCTGACATGAC
Downstream sequence
TAATTTGATATATTGTCTGAAATGGTAAGAACTTTAAATATTTTAAGTCTTTATATTTGAAATATGTGGCTGATACTATTTTATTACAGATAATGGGCTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate