Basic Information
VIS ID
TVIS30004832
Fusion event
HIV-IL2RB integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
37547695/37151655 (Hg38)
End
37547695/37151655 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
IL2RB
miRNAs that regulate target gene
hsa-mir-6834-5p ; hsa-mir-1294 ; hsa-mir-4316 ; hsa-mir-6747-5p ; hsa-mir-4455 ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-4300 ; hsa-mir-5591-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6875-5p ; hsa-mir-3126-5p ; hsa-mir-6732-5p
Nearest miRNA
hsa-mir-1286/Upstream/864748; hsa-let-7a-3/Downstream/692617;
Nearest TSS
ENST00000624155/Upstream/1665; ENST00000419128/Downstream/15102;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/53521, chr22-CpG: 33/Downstream/30537
Nearby gene
IL2RB(No orient, 1733)
Upstream sequence
ttttaacttgatgtgatctcatctatcatttctgctttggttgcatgtgctggtggggtattgctcaagaaatctttgcctagtcccatgtcctaaagag
Downstream sequence
tttccccaatgttccttttagtagtttcatagtttgaggtctcagatttaagtctttaatccatttggatttgatttttgtatatgaagagagatgaggg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate