Basic Information
VIS ID
TVIS30004869
Fusion event
HIV-HEMK1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
50621987/50584556 (Hg38)
End
50621987/50584556 (Hg38)
Orient
+
Location type
UTR3
Target gene
HEMK1
miRNAs that regulate target gene
hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-92a-2-5p ; hsa-mir-7110-5p ; hsa-mir-6881-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6835-5p ; hsa-mir-548p ; hsa-mir-3653-3p ; hsa-mir-505-5p ; hsa-mir-3185 ; hsa-mir-4311 ; hsa-mir-186-5p
Nearest miRNA
hsa-mir-12127/Upstream/311259; hsa-let-7g/Downstream/90524;
Nearest TSS
ENST00000440867/Upstream/7432; ENST00000486712/Downstream/16592;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/15015, chr3-CpG: 91/Downstream/26952
Upstream sequence
gaaggagtatcctggatttttcaggtaaactgagtataatcacaagggcctctgtaaaggaggcaggagtgtcagagtgacggaagaaaatgtatgtaac
Downstream sequence
aatggaagcagaggtcagagtgatgcaattgctggaggaagagccatgagccgaggaatgcagacagcctcttctcctctggggcctcaagaagaatgca
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate