Basic Information
VIS ID
TVIS30004886
Fusion event
HIV-AIMP1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q24
Reference genome
GRCh37/hg19
Start
107244361/106323204 (Hg38)
End
107244361/106323204 (Hg38)
Orient
+
Location type
Intronic
Target gene
AIMP1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-16-5p ; hsa-mir-340-5p ; hsa-mir-511-3p ; hsa-mir-568 ; hsa-mir-101-5p ; hsa-mir-223-5p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-4429 ; hsa-mir-320d ; hsa-mir-320c ; hsa-mir-320b ; hsa-mir-320a ; hsa-mir-186-5p ; hsa-mir-3133
Nearest miRNA
hsa-mir-12113/Upstream/4992790; hsa-mir-1243/Downstream/3165494;
Nearest TSS
ENST00000502981/Upstream/1709; ENST00000504132/Downstream/44231;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/426592, chr4-CpG: 61/Downstream/712194
Nearest cancer related gene
AIMP1(TSG, No orient, 0)
Upstream sequence
TTTCCTAAACTTATGCTTGTTCTTCAATATGTATTATAAAAGTCATATTTTATGTAACTAACTATTCCACTTATATTTTGCAAATAGTTAACAGATTTAT
Downstream sequence
CAACTCAGTAAAATTGTATTTTTTTCTCTTAGGCTAGGATTTATTATCTCTATTTTCAAAATTACTGTTATTCTTAGAAGATTTTTTATATGTTTCTGTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate