Basic Information
VIS ID
TVIS30004917
Fusion event
HIV-SERPINB1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p25.2
Reference genome
GRCh37/hg19
Start
2838827/2838593 (Hg38)
End
2838827/2838593 (Hg38)
Orient
+
Location type
Exonic
Target gene
SERPINB1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-34a-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-6720/Upstream/1448182; hsa-mir-10398/Downstream/15438;
Nearest TSS
ENST00000381078/Upstream/594; ENST00000437718/Downstream/3255;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/72052, chr6-CpG: 55/Downstream/2946
Upstream sequence
GAAAATATCTGCACTGTCTAGTGGGGTTTTAGAATGTGAAGGGCAAAGTACTTACAGGAAGGAAATTGTAAGTTTTCTCTCCATATAATCTATTAGCAAG
Downstream sequence
TTTCAGAATATAAGACGCTCCACGTTTGTTGATATCAGCATTCAGACTCTGGAATCTTGAATGAACCTCTTCAACCGTGTTGAAATGGAAAGTCTAAAAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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