Basic Information
VIS ID
TVIS30004943
Fusion event
HIV-MAP3K4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q26
Reference genome
GRCh37/hg19
Start
161472968/161051936 (Hg38)
End
161472968/161051936 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6E
Target gene
MAP3K4
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-148a-3p ; hsa-mir-93-5p ; hsa-mir-92a-3p ; hsa-mir-199a-3p ; hsa-mir-199b-3p ; hsa-mir-1245a ; hsa-mir-3123 ; hsa-mir-3129-5p ; hsa-mir-3691-3p ; hsa-mir-6073 ; hsa-mir-8062 ; hsa-mir-8079 ; hsa-mir-144-3p ; hsa-mir-101-3p
Nearest miRNA
hsa-mir-10398/Upstream/2287183; hsa-mir-1913/Downstream/5457418;
Nearest TSS
ENST00000381078/Upstream/17578; ENST00000542851/Downstream/21393;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/59404, chr6-CpG: 76/Downstream/593949
Nearest cancer related gene
MAP3K4(TSG, No orient, 0)
Upstream sequence
cttttTTGTTTGTATTATTACTATTACTGttttagagacaagatctcactacgttgcccaggctggactcaaactcgtgggctaaaacagtcctcctgcc
Downstream sequence
ttagcctcctgagtagcttgtattacTTTTTATTGTTGTATTCTTATTTTTAATGTTTTTTCAAACATTCTTGATCTGCGGATGCATATCCCAGGGTTTC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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