VISDB Viral Integration Site DataBase

VIS ID

TVIS30004962

Fusion event

HIV-EZH2 integration

Validated

No

Detection method

QiaQuick PCR and Sequencing

Data source

download(RID)

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Normal

Reported year

2013

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr7

Cytoband

q36.1

Reference genome

Start

End

148543732/148846640 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-214-3p ; hsa-mir-101-3p ; hsa-mir-26a-5p ; hsa-mir-199a-5p ; hsa-mir-217 ; hsa-mir-98-5p ; hsa-mir-124-3p ; hsa-mir-25-3p ; hsa-mir-30d-5p ; hsa-mir-138-5p ; hsa-mir-193b-3p ; hsa-mir-92b-3p ; hsa-mir-484 ; hsa-mir-320a ; hsa-mir-93-5p ; hsa-let-7a-5p ; hsa-mir-185-5p ; hsa-mir-200a-3p ; hsa-mir-200b-3p ; hsa-mir-429 ; hsa-mir-26b-5p ; hsa-mir-708-5p ; hsa-let-7e-5p ; hsa-mir-144-3p ; hsa-let-7c-5p ; hsa-mir-3679-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-1236-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-1224-3p ; hsa-mir-6865-3p ; hsa-mir-320c ; hsa-mir-125a-3p ; hsa-mir-340-3p ; hsa-mir-137 ; hsa-mir-126-3p ; hsa-let-7b-5p ; hsa-mir-498 ; hsa-mir-27a-3p ; hsa-mir-101-5p

Nearest miRNA

hsa-mir-10399/Upstream/1468519; hsa-mir-153-2/Downstream/2391781;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/63228, chr7-CpG: 177/Downstream/36763

Nearest cancer related gene

EZH2(OG, No orient, 0)

Upstream sequence

CTTGGTTTAAGATTTCCGTTCTTTCCAAAATTTTCTGACGATTGGAACTAAACATACTCTTAAAAAAAAAAATGAAGGAGAGGAAAGGAGAAATTGTTCA

Downstream sequence

TTGTTAGAAAATGTATAACACCTGTAAAGCAGGTTAAAAATCTAGTGTATCCTCAAAAATATCAAGAACATTTTCTTAGGTGCATATAGATTTTACACTA