Basic Information
VIS ID
TVIS30004978
Fusion event
HIV-AZIN1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
103863636/102851408 (Hg38)
End
103863636/102851408 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8A
Target gene
AZIN1
miRNAs that regulate target gene
hsa-mir-30b-5p ; hsa-mir-17-5p ; hsa-mir-433-3p ; hsa-mir-744-3p ; hsa-mir-192-3p ; hsa-mir-633 ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-186-5p ; hsa-mir-3149 ; hsa-mir-578 ; hsa-mir-4677-5p ; hsa-mir-297 ; hsa-mir-675-3p ; hsa-mir-2110 ; hsa-mir-22-5p ; hsa-mir-2116-5p ; hsa-mir-124-5p ; hsa-mir-567 ; hsa-mir-6780b-5p ; hsa-mir-4271 ; hsa-mir-4725-3p ; hsa-mir-643 ; hsa-mir-380-3p ; hsa-mir-4495 ; hsa-mir-4506 ; hsa-mir-411-3p ; hsa-mir-379-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30a-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-12123/Upstream/725893; hsa-mir-10400/Downstream/303206;
Nearest TSS
ENST00000518652/Upstream/15933; ENST00000519337/Downstream/3047;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/40373, chr8-CpG: 183/Downstream/11586
Upstream sequence
GCAGAGCTCATTGCCTGCCTGTCCACTACTCACCCAAGGAAAACATATAGAATACATGTGCAATACAGTAATTGCAACCAAGACCAAGTTAAGCAGGTTA
Downstream sequence
TTAAGAAATCAGATGCTggccggacatggtggctcacgcctgtaatcccagcactttgggaggctgacgcaggtggatcatgagatcaggagttccagac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate