Basic Information
VIS ID
TVIS30004987
Fusion event
HIV-DGAT1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
145544024/144320361 (Hg38)
End
145544024/144320361 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
DGAT1
miRNAs that regulate target gene
hsa-mir-125b-5p ; hsa-mir-26b-5p ; hsa-mir-484 ; hsa-mir-183-5p ; hsa-mir-4468 ; hsa-mir-6849-3p ; hsa-mir-548q ; hsa-mir-5197-3p ; hsa-mir-2278 ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-5001-3p ; hsa-mir-4727-5p ; hsa-mir-6817-5p ; hsa-mir-4769-3p ; hsa-mir-3065-3p ; hsa-mir-3620-3p ; hsa-mir-6858-3p ; hsa-mir-6871-3p ; hsa-mir-10b-5p ; hsa-mir-10a-5p
Nearest miRNA
hsa-mir-1204/Upstream/3046; hsa-mir-10400/Downstream/73788;
Nearest TSS
ENST00000518652/Upstream/1637; ENST00000644270/Downstream/6306;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/28084, chr8-CpG: 158/Downstream/5960
Upstream sequence
GTTGGGGAGAATACACAGTGCTGCCTGGGCTGGACAAGGCCCAACCTGGGCCAGGAATGGGCTGCGTCTCCTGAGTGCTGGGCTGGCGCTGGGCCCACTG
Downstream sequence
TCCTCCTGCCTGGCCAGCTTCTCAGCCACCAGGACTCGTGGGCCTCCACAGCTGGCCACCCCCAGGGAACCTTCTAGGACCATGGGCGGTGGGGGATGTG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate