Basic Information
VIS ID
TVIS30004995
Fusion event
HIV-TLE4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
82220119/79605204 (Hg38)
End
82220119/79605204 (Hg38)
Orient
-
Location type
Intronic
Target gene
TLE4
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-548b-3p ; hsa-mir-335-5p ; hsa-mir-186-5p ; hsa-mir-103a-3p ; hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-let-7d-5p ; hsa-mir-193b-3p ; hsa-mir-221-3p ; hsa-mir-195-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p
Nearest miRNA
hsa-mir-101-2/Upstream/8795120; hsa-let-7a-1/Downstream/4364544;
Nearest TSS
ENST00000422679/Upstream/24977; ENST00000493163/Downstream/47389;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/31559, chr9-CpG: 255/Downstream/2082020
Upstream sequence
AGGAAAGAGCTATTGGTAGAACTTGGATGTCTTAGTAATCAGAGTAATCAGGTTCTCTGACCGGTTCCACCTTGTTCTGTGCAGGCTGAAAGTAAGCTCT
Downstream sequence
CTAGAGAAAGTAATTTTCTTTCTCTGCTCCTTCTGACATCCCACTTTTCCCTCCCATCCTTCCTTTCTATTTTCCCTGCCTCTCCCCTCTGGTAGAACTG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate