VISDB Viral Integration Site DataBase

VIS ID

TVIS30005012

Fusion event

HIV-NOTCH1 integration

Validated

No

Detection method

QiaQuick PCR and Sequencing

Data source

download(RID)

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Normal

Reported year

2013

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr9

Cytoband

q34.3

Reference genome

Start

End

139437815/136543363 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-27b-3p ; hsa-mir-24-3p ; hsa-mir-23b-3p ; hsa-mir-34a-5p ; hsa-mir-30a-5p ; hsa-mir-326 ; hsa-mir-129-5p ; hsa-mir-144-3p ; hsa-mir-449a ; hsa-mir-34b-3p ; hsa-mir-34c-5p ; hsa-mir-10b-5p ; hsa-mir-181a-5p ; hsa-mir-30b-5p ; hsa-mir-139-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-5088-3p ; hsa-mir-335-3p ; hsa-mir-627-3p ; hsa-mir-6761-3p ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-1277-3p ; hsa-mir-363-3p ; hsa-mir-9-5p ; hsa-mir-410-3p ; hsa-mir-101-3p ; hsa-mir-935 ; hsa-mir-30a-3p ; hsa-mir-146a-5p ; hsa-mir-296-5p

Nearest miRNA

hsa-let-7a-1/Upstream/23737; hsa-mir-126/Downstream/2810;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/9288, chr9-CpG: 263/Downstream/1226

Nearest cancer related gene

NOTCH1(TSG, No orient, 0)

Upstream sequence

CTGTGCCTAGAGGAGGCATCACCCGCCTAGAGGAGGTATCACCACCCAGAGGAGGCATCACCCACCTAGAGGAGGTATCACCACCCAGAGGAGGCATCAC

Downstream sequence

CCACCCAGGAGGTGGCATCACCCGTGCCCAGAGGAGGCATCACGCACCCAGAGGAGGCATCACCCGCCCAGGAGGTGGCATCACCTGTGCCCAGAGGAGG