Basic Information
VIS ID
TVIS30005080
Fusion event
HIV-UBE4B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.22
Reference genome
GRCh37/hg19
Start
10152065/10092007 (Hg38)
End
10152065/10092007 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
UBE4B
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-423-3p ; hsa-mir-92a-3p ; hsa-mir-6885-3p ; hsa-mir-3926 ; hsa-mir-1251-3p ; hsa-mir-4753-5p ; hsa-mir-9-5p ; hsa-mir-7111-5p ; hsa-mir-5698 ; hsa-mir-6870-5p ; hsa-mir-4723-5p ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-4668-5p ; hsa-mir-3202 ; hsa-mir-3148 ; hsa-mir-3179 ; hsa-mir-873-5p ; hsa-mir-1182 ; hsa-mir-1178-5p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-6783-5p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-2681-5p ; hsa-mir-607 ; hsa-mir-29b-2-5p ; hsa-mir-580-3p ; hsa-mir-3671 ; hsa-mir-584-5p ; hsa-mir-6798-3p ; hsa-mir-186-3p ; hsa-mir-4762-5p ; hsa-mir-758-5p ; hsa-mir-218-2-3p ; hsa-mir-501-5p ; hsa-mir-500a-5p ; hsa-mir-651-3p
Nearest miRNA
hsa-mir-12136/Upstream/124549; hsa-mir-101-1/Downstream/1937151;
Nearest TSS
ENST00000473358/Upstream/58411; ENST00000462658/Downstream/8854;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/58661, chr1-CpG: 156/Downstream/117950
Nearest cancer related gene
UBE4B(TSG, No orient, 0)
Upstream sequence
cctgactaattttttaagtattttgtagagacagggtctctgtgttgcccaggctggtctcaaactcctggcctcaagtgatcctctctccttgactccc
Downstream sequence
caaaagtgctgggattacagatgtgaggcacGACTGACCATCAGTATTTTAAATTTAAGAAAGGAGAGAAATGGGTTAtggtggcatatgttctttgttt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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