Basic Information
VIS ID
TVIS30005112
Fusion event
HIV-EIF4G3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.12
Reference genome
GRCh37/hg19
Start
21260083/20933590 (Hg38)
End
21260083/20933590 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
EIF4G3
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-24-3p ; hsa-mir-16-5p ; hsa-mir-221-3p ; hsa-mir-17-5p ; hsa-mir-3613-3p ; hsa-mir-543 ; hsa-mir-136-5p ; hsa-mir-377-5p ; hsa-mir-218-5p ; hsa-mir-548c-3p ; hsa-mir-4724-3p ; hsa-mir-6813-3p ; hsa-mir-3200-3p
Nearest miRNA
hsa-mir-12136/Upstream/299802; hsa-mir-101-1/Downstream/54724;
Nearest TSS
ENST00000473358/Upstream/85645; ENST00000416959/Downstream/7808;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/145962, chr1-CpG: 77/Downstream/243032
Upstream sequence
ctaaaaatacaaaaattatccgggcgtggtggtgcgcacctgtaatcccagctactcagggggctgagggaggagaatcacttgaacctgggaggcggaa
Downstream sequence
ggttgcagtgagctgagatcacaccaccgcactccagcctgggcaacagagtgagactctatcttgtggggggaaaaacaaaaacaaaaacagggcacct
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate