Basic Information
VIS ID
TVIS30005206
Fusion event
HIV-MED8 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.2
Reference genome
GRCh37/hg19
Start
43850442/43384771 (Hg38)
End
43850442/43384771 (Hg38)
Orient
+
Location type
UTR3
Target gene
MED8
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-98-5p ; hsa-mir-615-3p ; hsa-mir-186-5p ; hsa-mir-877-3p ; hsa-mir-629-3p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-3611 ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-4795-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-5088-3p ; hsa-mir-3938 ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p
Nearest miRNA
hsa-mir-12136/Upstream/20056; hsa-mir-101-1/Downstream/63768;
Nearest TSS
ENST00000473358/Upstream/16697; ENST00000436713/Downstream/342;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/16305, chr1-CpG: 50/Downstream/4933
Upstream sequence
AGATTAGGGTAAGTTCTGGATCAAGGACTGTGGAGGGTGGTGGGGAGAAGGATCTGTAGAaactatcatttattgaatacccattatttcatatactgta
Downstream sequence
ctaagtgctttacattcatttcctcattttaatcctcacaacaaccctatgaggtaggtattatcaccatttacaaatgagaaacaggctcagaaaaatt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate