Basic Information
VIS ID
TVIS30005217
Fusion event
HIV-EIF2B3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.1
Reference genome
GRCh37/hg19
Start
45446637/44980965 (Hg38)
End
45446637/44980965 (Hg38)
Orient
+
Location type
Intronic
Target gene
EIF2B3
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-615-3p ; hsa-mir-320a
Nearest miRNA
hsa-mir-12136/Upstream/435413; hsa-mir-101-1/Downstream/6078872;
Nearest TSS
ENST00000473358/Upstream/54310; ENST00000461035/Downstream/5621;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/137478, chr1-CpG: 38/Downstream/5385
Upstream sequence
ACACAGCAATAGAGTACTCCTACATTCCTTAAAGAAGGCAGTCTTCAGCCAACGAGTTCTAGTCACCCTCTCTCATTCTCATAACGCTGACAAATCATGG
Downstream sequence
GGATCAAATCTCCTAAAAGTTTTATGAGTTCACAGCTCACTTTGTCATAGCTCACCTTCAAATCCAACACGCTCAAGCAGGTTCAATGGGTACCAAATTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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