Basic Information
VIS ID
TVIS30005231
Fusion event
HIV-EPS15 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
GRCh37/hg19
Start
51930111/51464439 (Hg38)
End
51930111/51464439 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1B
Target gene
EPS15
miRNAs that regulate target gene
hsa-mir-374a-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-181d-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p
Nearest miRNA
hsa-mir-12136/Upstream/404336; hsa-mir-101-1/Downstream/371905;
Nearest TSS
ENST00000473358/Upstream/2718; ENST00000415031/Downstream/887;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/119424, chr1-CpG: 66/Downstream/54266
Upstream sequence
agcgattctcctgcctcagcctcccgagtagctgggattataggcgcctgccaccacacccagctaattttcttgtacttttagtagacacggggtttca
Downstream sequence
ctatgttggccaggctggtctcgaactcctgacctcatgatctgcccgcctcaccctcccaaagtgctgggattacaggcatgagccacaaataaatttt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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