Basic Information
VIS ID
TVIS30005232
Fusion event
HIV-EPS15 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
GRCh37/hg19
Start
51983147/51517475 (Hg38)
End
51983147/51517475 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1B
Target gene
EPS15
miRNAs that regulate target gene
hsa-mir-374a-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-181d-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p
Nearest miRNA
hsa-mir-12136/Upstream/457372; hsa-mir-101-1/Downstream/318869;
Nearest TSS
ENST00000473358/Upstream/52149; ENST00000415031/Downstream/834;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/172460, chr1-CpG: 66/Downstream/1230
Upstream sequence
ATGGCTATAAAACTGACAGAGCTTGAAGCAATTCTCCAGAGATGAATGATGTAAATAGAAGCTAAAAACATGGTATTACCCAGGGAGAGAATAAAGTATG
Downstream sequence
CACACAACTGAGAAGCAATTTTACGGAAGTCTTTAAGAGCACAAAATCTTCAAGGGAAAACTCCTGCCAGAATTGGCCAACAGAGCCAGAAAACAACAGC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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