Basic Information
VIS ID
TVIS30005252
Fusion event
HIV-ITGB3BP integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
GRCh37/hg19
Start
63944792/63479121 (Hg38)
End
63944792/63479121 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
ITGB3BP
miRNAs that regulate target gene
hsa-mir-9-5p ; hsa-mir-150-3p ; hsa-mir-4536-5p ; hsa-mir-299-3p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-7161-3p ; hsa-mir-224-5p ; hsa-mir-3156-5p
Nearest miRNA
hsa-mir-12132/Upstream/152137; hsa-mir-101-1/Downstream/1100726;
Nearest TSS
ENST00000473358/Upstream/21426; ENST00000480886/Downstream/11093;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/110971, chr1-CpG: 99/Downstream/114145
Upstream sequence
ATATAAGAAAAAATAATCTTTTGAATAAAATTTCCACTGAAGGTTGGTATATTAAAGAGAAATCAAATATGATTCTATAATTAGGTTAAAATGCATTAGT
Downstream sequence
AAACTTTATTAGATAAAGGATACTTTCATCAAATATTTTAATCAATGATATCATATAAAGGCTTCCAGTTTGCATTATTCCACCTTTATTTTTTTTCTCA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate