Basic Information
VIS ID
TVIS30005257
Fusion event
HIV-MIER1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
GRCh37/hg19
Start
67406329/66940646 (Hg38)
End
67406329/66940646 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
MIER1
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-30e-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-580-3p ; hsa-mir-4324 ; hsa-mir-4251 ; hsa-mir-20b-3p ; hsa-mir-3137 ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-3686 ; hsa-mir-190a-3p ; hsa-mir-298 ; hsa-mir-338-3p ; hsa-mir-4530 ; hsa-mir-922 ; hsa-mir-5586-5p ; hsa-mir-410-3p ; hsa-mir-5197-3p ; hsa-mir-450b-5p ; hsa-mir-4511 ; hsa-mir-4696
Nearest miRNA
hsa-mir-101-1/Upstream/312129; hsa-mir-11399/Downstream/1242872;
Nearest TSS
ENST00000473358/Upstream/7994; ENST00000493357/Downstream/18265;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/9846, chr1-CpG: 59/Downstream/113216
Upstream sequence
TTGAATAGGATCAAGTTTTAGGTTCTGAGCACACATCTAGGATTTTTGTATTCTTTCTCAAATACAGTACATATTCATTTTTTCCTAACTTagagattgc
Downstream sequence
aaacctgtgatctttgaatcagatctgtgccacaaatttttgtttggccactgtagtgatctttaagaatattttatatatgaaatctggatttagggtt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate