Basic Information
VIS ID
TVIS30005296
Fusion event
HIV-DPYD integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
98018362/97552806 (Hg38)
End
98018362/97552806 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1M
Target gene
DPYD
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-302b-3p ; hsa-mir-494-5p
Nearest miRNA
hsa-mir-101-1/Upstream/3009027; hsa-mir-11399/Downstream/492436;
Nearest TSS
ENST00000473358/Upstream/287360; ENST00000431362/Downstream/168848;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/830543, chr1-CpG: 47/Downstream/367827
Upstream sequence
CCTCATTAAAAATCAAACAATTCTTTGATACTCTATTCTAAAATAGAAAAAGGATTTTCTTTCATATTAAAAATCATCTCAGTCTCCTTTTGAAAATTAA
Downstream sequence
CTACCAAATTTCCTCCTGCTCATTTTGGAGACCTTCAAGTTTAACATGTTCCTAATTTCATTCCAGAAATAAAAAGAAAAAGCTGAGAGATCACACAGCT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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