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Viral Integration Site DataBase
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TVIS30005331
Basic Information
VIS ID
TVIS30005331
Fusion event
HIV-NRAS integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
115247691/114705070 (Hg38)
End
115247691/114705070 (Hg38)
Orient
+
Location type
UTR3
Target gene
NRAS
miRNAs that regulate target gene
hsa-let-7a-5p
;
hsa-let-7b-5p
;
hsa-mir-20a-5p
;
hsa-let-7c-5p
;
hsa-mir-145-5p
;
hsa-mir-148b-3p
;
hsa-mir-124-3p
;
hsa-mir-98-5p
;
hsa-mir-877-3p
;
hsa-mir-214-3p
;
hsa-mir-519c-5p
;
hsa-mir-519b-5p
;
hsa-mir-523-5p
;
hsa-mir-518f-5p
;
hsa-mir-526a
;
hsa-mir-520c-5p
;
hsa-mir-518e-5p
;
hsa-mir-518d-5p
;
hsa-mir-522-5p
;
hsa-mir-519a-5p
;
hsa-mir-4686
;
hsa-mir-2681-5p
;
hsa-mir-2113
;
hsa-mir-3123
;
hsa-mir-3925-5p
;
hsa-mir-4468
;
hsa-mir-543
;
hsa-mir-4480
;
hsa-mir-2276-3p
;
hsa-mir-4772-3p
;
hsa-mir-7109-3p
;
hsa-mir-3662
;
hsa-mir-513a-5p
;
hsa-mir-1193
;
hsa-mir-3613-3p
;
hsa-mir-2392
;
hsa-mir-7161-5p
;
hsa-mir-548u
;
hsa-mir-27b-3p
;
hsa-mir-27a-3p
;
hsa-mir-6833-5p
;
hsa-mir-218-5p
;
hsa-mir-8068
;
hsa-mir-3190-3p
;
hsa-mir-3650
;
hsa-mir-6077
;
hsa-mir-2467-3p
;
hsa-mir-7-5p
;
hsa-mir-7114-5p
;
hsa-mir-4257
;
hsa-mir-548b-3p
;
hsa-mir-1303
;
hsa-mir-3143
;
hsa-mir-4537
;
hsa-mir-520g-5p
;
hsa-mir-2278
;
hsa-mir-219b-3p
;
hsa-mir-922
;
hsa-mir-92b-3p
;
hsa-mir-367-3p
;
hsa-mir-32-5p
;
hsa-mir-363-3p
;
hsa-mir-25-3p
;
hsa-mir-92a-3p
;
hsa-mir-5585-3p
;
hsa-mir-3160-5p
;
hsa-mir-642b-3p
;
hsa-mir-642a-3p
;
hsa-mir-4774-5p
;
hsa-mir-4490
;
hsa-mir-4719
;
hsa-mir-425-5p
;
hsa-mir-944
;
hsa-mir-26a-5p
;
hsa-mir-181a-5p
;
hsa-mir-98-3p
Nearest miRNA
hsa-mir-101-1/Upstream/1822941; hsa-mir-1182/Downstream/1854954;
Nearest TSS
ENST00000473358/Upstream/9452;
ENST00000468191/Downstream/11824;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/34706
,
chr1-CpG: 35/Downstream/75384
Nearest cancer related gene
NRAS
(OG, No orient, 0)
Upstream sequence
TTCCCTAATTTTCCTTGCTTCTTATAATTTATTAGCAGAGATGAATTACAAGAAGCAGAACGCACCATTTTTTGGTTCTTGGTTGTAGCTGCCAACTTAG
Downstream sequence
GAGTTCATGACTATAAATATAAAGCAAATATGATTATGCTCACAAGCTCTGGAATGGTAAAAAAACCCCACATATCTCTAAAGTGTTTCTCTATCCTTGC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Central Memory CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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