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TVIS30005375
Basic Information
VIS ID
TVIS30005375
Fusion event
HIV-IL6R integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
154385063/154412587 (Hg38)
End
154385063/154412587 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1F
Target gene
IL6R
miRNAs that regulate target gene
hsa-mir-23a-3p
;
hsa-mir-124-3p
;
hsa-mir-125b-5p
;
hsa-mir-98-5p
;
hsa-mir-451a
;
hsa-mir-34c-5p
;
hsa-mir-34b-3p
;
hsa-mir-34a-5p
;
hsa-mir-619-5p
;
hsa-mir-3619-3p
;
hsa-mir-6807-5p
;
hsa-mir-5095
;
hsa-mir-7151-3p
;
hsa-mir-4529-5p
;
hsa-mir-1292-3p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-4793-5p
;
hsa-mir-6504-3p
;
hsa-mir-4438
;
hsa-mir-335-3p
;
hsa-mir-5096
;
hsa-mir-6809-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-4753-3p
;
hsa-mir-7156-3p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-4284
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-1184
;
hsa-mir-4638-5p
;
hsa-mir-1307-3p
;
hsa-mir-1304-3p
;
hsa-mir-6741-3p
;
hsa-mir-4726-3p
;
hsa-mir-6764-5p
;
hsa-mir-1915-3p
;
hsa-mir-6840-3p
;
hsa-mir-6890-3p
;
hsa-mir-509-5p
;
hsa-mir-509-3-5p
;
hsa-mir-4418
;
hsa-mir-7641
;
hsa-mir-2052
;
hsa-mir-4695-3p
;
hsa-mir-4330
;
hsa-mir-5680
;
hsa-mir-5197-5p
;
hsa-mir-1537-3p
;
hsa-mir-548ay-3p
;
hsa-mir-548at-3p
;
hsa-mir-221-5p
;
hsa-let-7c-3p
;
hsa-let-7a-5p
;
hsa-let-7b-5p
;
hsa-let-7c-5p
;
hsa-let-7d-5p
;
hsa-let-7e-5p
;
hsa-let-7f-5p
;
hsa-let-7g-5p
;
hsa-let-7i-5p
;
hsa-mir-126-5p
;
hsa-mir-1277-3p
;
hsa-mir-202-3p
;
hsa-mir-219a-1-3p
;
hsa-mir-331-5p
;
hsa-mir-4458
;
hsa-mir-4500
;
hsa-mir-4678
;
hsa-mir-4738-3p
;
hsa-mir-4795-3p
;
hsa-mir-495-3p
;
hsa-mir-510-3p
;
hsa-mir-515-5p
;
hsa-mir-519d-5p
;
hsa-mir-519e-5p
;
hsa-mir-548ae-3p
;
hsa-mir-548ah-3p
;
hsa-mir-548aj-3p
;
hsa-mir-548am-3p
;
hsa-mir-548aq-3p
;
hsa-mir-548j-3p
;
hsa-mir-548x-3p
;
hsa-mir-5582-3p
;
hsa-mir-5688
;
hsa-mir-5695
;
hsa-mir-570-3p
;
hsa-mir-630
;
hsa-mir-6509-5p
;
hsa-mir-653-5p
Nearest miRNA
hsa-mir-101-1/Upstream/218844; hsa-mir-1182/Downstream/563106;
Nearest TSS
ENST00000473358/Upstream/6023;
ENST00000476006/Downstream/16756;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/6618
,
chr1-CpG: 196/Downstream/89044
Upstream sequence
cctcaggtgatccacccaccttggcctcccaaagtgctgggattacagacgtgagctaccgcgcccggccTTTAAAAGCCTATTTTGATGGGAGGAGGGG
Downstream sequence
GATGCTATAATGTGAGGACTTTCTCCCAGAAAAGGAGAGAGAGGCACTAATGCAGTGGGGATAATAATTAAAATCGCTTAACATTttttttgaaagatta
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Central Memory CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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