Basic Information
VIS ID
TVIS30005385
Fusion event
HIV-GBA integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q22
Reference genome
GRCh37/hg19
Start
155212576/155242785 (Hg38)
End
155212576/155242785 (Hg38)
Orient
-
Location type
Intronic
Target gene
GBA
miRNAs that regulate target gene
hsa-mir-191-5p ; hsa-mir-4298 ; hsa-mir-1302 ; hsa-mir-4795-5p ; hsa-mir-4648 ; hsa-mir-1236-3p ; hsa-mir-4735-5p ; hsa-mir-6733-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p
Nearest miRNA
hsa-mir-101-1/Upstream/47513; hsa-mir-1182/Downstream/103565;
Nearest TSS
ENST00000473358/Upstream/1510; ENST00000467204/Downstream/1821;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/15042, chr1-CpG: 39/Downstream/7506
Upstream sequence
cggctcaagcaattgccctgcctcagcctcctgagtagctgggattacaggagcccaccaccatgcccagctaatttttgtatttttagtagagatgggg
Downstream sequence
tttcaccatgttggccaggctggtctcgaacccctgacctcaggtgatccaccagcctcagcctcccaaggtgttgggattatagcaatgagccaccaca
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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