Basic Information
VIS ID
TVIS30005404
Fusion event
HIV-ARHGEF2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q22
Reference genome
GRCh37/hg19
Start
155929523/155959732 (Hg38)
End
155929523/155959732 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARHGEF2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-96-5p ; hsa-mir-877-3p ; hsa-mir-744-5p ; hsa-mir-423-3p ; hsa-mir-320a ; hsa-mir-4728-5p ; hsa-mir-328-3p ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6851-3p ; hsa-mir-6775-3p ; hsa-mir-1291 ; hsa-mir-6799-3p ; hsa-mir-3173-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-7845-5p ; hsa-mir-942-3p ; hsa-mir-4475 ; hsa-mir-194-3p
Nearest miRNA
hsa-mir-101-1/Upstream/8396; hsa-mir-1182/Downstream/460609;
Nearest TSS
ENST00000473358/Upstream/7011; ENST00000610146/Downstream/2225;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/8625, chr1-CpG: 87/Downstream/18155
Nearest cancer related gene
ARHGEF2(OG, No orient, 0)
Upstream sequence
ctcctgagttcaagcgattctcatgcctcagcctcccaagtagctgtggctacaggtgaatgctgccatgcctggctaatttttgtatttttagtagaga
Downstream sequence
tggggtttcaccatcttggccaggctggtctcgaattccggacctcaggcgatctgcctgcctgattcagcctcccaaagtgctgagattatagggatga
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate