Basic Information
VIS ID
TVIS30005456
Fusion event
HIV-UCHL5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
192995819/193026689 (Hg38)
End
192995819/193026689 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1K
Target gene
UCHL5
miRNAs that regulate target gene
hsa-mir-5581-3p ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-3185 ; hsa-mir-6872-3p ; hsa-mir-1322 ; hsa-mir-9500 ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-5584-5p ; hsa-mir-2681-5p ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-6883-3p ; hsa-mir-539-3p ; hsa-mir-485-3p ; hsa-mir-454-5p ; hsa-mir-6512-5p ; hsa-mir-1-5p
Nearest miRNA
hsa-mir-101-1/Upstream/310299; hsa-mir-1182/Downstream/109814;
Nearest TSS
ENST00000473358/Upstream/2749; ENST00000469214/Downstream/2620;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/217621, chr1-CpG: 94/Downstream/32402
Upstream sequence
aacaccaaatgctaaaaaggatgcagaggaactagaccgttcatatattgctggtagaaatataaaatggtacagtcactctggaaaagagtttggtagt
Downstream sequence
ttcttaaaaaaaaaaaaaaatatccatttaccatgcaacccagcaatgcaacacataggcatttatcccagagaaatgaaaacttgcagtcacaaaaaat
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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