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VISDB
Viral Integration Site DataBase
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TVIS30005457
Basic Information
VIS ID
TVIS30005457
Fusion event
HIV-CDC73 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
193117194/193148064 (Hg38)
End
193117194/193148064 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1K
Target gene
CDC73
miRNAs that regulate target gene
hsa-mir-155-5p
;
hsa-mir-23b-3p
;
hsa-mir-100-5p
;
hsa-mir-495-3p
;
hsa-mir-5688
;
hsa-mir-5692a
;
hsa-mir-4635
;
hsa-mir-186-5p
;
hsa-mir-3133
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-5196-5p
;
hsa-mir-4747-5p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-4733-5p
;
hsa-mir-5096
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6875-3p
;
hsa-mir-197-3p
;
hsa-mir-124-5p
;
hsa-mir-1226-3p
;
hsa-mir-634
;
hsa-mir-665
;
hsa-mir-6771-5p
;
hsa-mir-7160-5p
;
hsa-mir-6797-3p
;
hsa-mir-4722-5p
;
hsa-mir-6076
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-1827
;
hsa-mir-7153-5p
;
hsa-mir-146b-5p
;
hsa-mir-4649-3p
;
hsa-mir-146a-5p
;
hsa-mir-6746-5p
;
hsa-mir-4768-3p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-6807-3p
;
hsa-mir-217
;
hsa-mir-6736-5p
;
hsa-mir-4701-3p
;
hsa-mir-1262
;
hsa-mir-6864-3p
;
hsa-mir-3672
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-542-3p
;
hsa-mir-661
;
hsa-mir-873-3p
;
hsa-mir-6776-5p
;
hsa-mir-766-3p
;
hsa-mir-372-5p
;
hsa-mir-371a-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-6742-3p
;
hsa-mir-6849-3p
;
hsa-mir-759
;
hsa-mir-3613-3p
;
hsa-mir-5586-3p
;
hsa-mir-4797-5p
Nearest miRNA
hsa-mir-101-1/Upstream/11481; hsa-mir-1182/Downstream/3434349;
Nearest TSS
ENST00000473358/Upstream/25594;
ENST00000477868/Downstream/38590;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/25970
,
chr1-CpG: 24/Downstream/3460514
Nearest cancer related gene
CDC73
(TSG, No orient, 0)
Upstream sequence
GGTAAGAATGCTTTACTGCTTTACAGTAGATTTAATGAAGTTGCCACTTATATTGCAGTGTAGTAACGTTGAAGACATCTTCACATTTTAAAATCAGTGG
Downstream sequence
ATTCTAAACCTTTTGCTCCTTTAGCATATCTGAAAGATGTGAAAGCCCTCCCCAACATTAAAAGTTACTTACTTCAGCAGTAATTCTTAACTGGAGCAGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Central Memory CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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