Basic Information
VIS ID
TVIS30005499
Fusion event
HIV-NVL integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.11
Reference genome
GRCh37/hg19
Start
224475135/224287433 (Hg38)
End
224475135/224287433 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
NVL
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-let-7b-5p ; hsa-mir-186-5p ; hsa-mir-138-5p ; hsa-mir-25-3p
Nearest miRNA
hsa-mir-101-1/Upstream/30323; hsa-mir-1182/Downstream/110794;
Nearest TSS
ENST00000473358/Upstream/17518; ENST00000477413/Downstream/6908;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/103380, chr1-CpG: 37/Downstream/42594
Upstream sequence
taataagttctggtatttgatagcacggtagggaaattatatttcaaaacagctagaagaaaaaagtatatttcaaaacagctagaagaaaaaaagtata
Downstream sequence
atgttcccaacacaaagaaaacataaacattagaggtgatgaatatcccaattaccctgacttcatcaatacacatttaatatatgtatcaaaatatcac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate